For a complete list of publications, check Dr. Oakes’ ORCiD or Google Scholar.
PUBLICATIONS
| Kapnick SM, Gosselin EA, Tsai SJ, Oakes RS, Habibabady ZA, Ackun-Farmmer MA, Carey ST, Shah SA, Shen R, Froimchuk E, Eppler HB, Bridgeman CJ, Yanes AA, McIlvaine RA, Noshin M, Tostanoski LH, Black SK, Zeng X, Azimzadeh A, Pierson RN, Bromberg JS, Jewell CM. Local control of T cell fate in lymph nodes safely and durably reverses myelin-driven autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 2025; 122 (45) e2409563122. doi: 10.1073/pnas.2409563122. |
| Piao W, Wu L, Xiong Y, Zapas GC, Pettit S, Paluskievicz C, Oakes RS, Kong D, Sleeth M, Hippen K, Lee Y, Li L, Willson-Shirkey M, Kensiski A, Alvi A, Jewell CM, Blazar BW, Bromberg JS. Regulatory T cells crosstalk with tumor and endothelium through lymphotoxin signaling. Nature Communications. 2024; 15:10468. doi: 10.1038/s41467-024-54874-y |
| Ackun-Farmmer MA, Willson-Shirkey M, Oakes RS, Shah SA, Edwards CM, Kapnick SM, Carey ST, Yanes AA, Bromberg JS, Jewell CM. Engineered immune constructs alter antigen-specific immune tolerance and confer durable protection in myelin-driven autoimmunity. ACS Nano. 2024; 18(46):31780–31793. doi: 10.1021/acsnano.4c06667 |
| Shah SA, Oakes RS, Jewell CM. Advancing immunotherapy using biomaterials to control tissue, cellular, and molecular level immune signaling in skin. Advanced Drug Delivery Reviews. 2024; 209:115315. doi: 10.1016/j.addr.2024.115315 |
| Price SL, Oakes RS, Gonzalez RJ, Edwards C, Brady A, DeMarco JK, von Andrian UH, Jewell CM, Lawrenz MB. Microneedle array delivery of Yersinia pestis recapitulates bubonic plague. iScience. 2024; 27:108600. doi: 10.1016/j.isci.2023.108600 |
| Bridgeman CJ, Shah SA, Oakes RS, Jewell CM. Dissecting regulatory T cell expansion using polymer microparticles presenting defined ratios of self-antigen and regulatory cues. Frontiers in Bioengineering and Biotechnology. 2023; 11:1184938. doi: 10.3389/fbioe.2023.1184938 |
| Edwards C, Oakes RS, Jewell CM. Tuning innate immune function using microneedles containing multiple classes of toll-like receptor agonists. Nanoscale. 2023; 15:8662–8674. doi: 10.1039/D3NR00333G |
| Jewell CM, Miljković MD, Oakes RS. Transforming bioengineering with unbiased teams and tools. Nature Reviews Bioengineering. 2023; 1:538–540. doi: 10.1038/s44222-023-00058-0 |
| Gammon JM‡, Carey SC‡, Saxena V, Eppler HB, Tsai SJ, Paluskievicz C, Xiong Y, Li L, Ackun-Farmmer MA, Tostanoski LH, Gosselin EA, Yanes AA, Zeng X, Oakes RS, Bromberg JS*, Jewell CM*. Engineering the lymph node environment to promote antigen-specific efficacy in type 1 diabetes and allogeneic islet transplantation. Nature Communications. 2023; 14(1):681. doi: 10.1038/s41467-023-36225-5 |
| Bookstaver ML‡, Zeng Q‡, Oakes RS, Kapnick SM, Saxena V, Edwards C, Venkataraman N, Black SK, Zeng X, Froimchuk E, Gebhardt T, Bromberg JS, Jewell CM. Self-assembly of immune signals to program innate immunity through rational adjuvant design. Advanced Science. 2022; 2202393. doi: 10.1002/advs.202202393 |
| Shah SA, Oakes RS, Kapnick SM, Jewell CM. Mapping the Mechanical and Immunological Profiles of Polymeric Microneedles to Enable Vaccine and Immunotherapy Applications. Frontiers in Immunology. 2022; 13: 843355. doi: 10.3389/fimmu.2022.843355 |
| Oakes RS, Tostanoski LH, Kapnick SM, Froimchuk E, Black SK, Zeng X, Jewell CM. Exploiting Rational Assembly to Map Distinct Roles of Regulatory Cues during Autoimmune Therapy. ACS Nano. 2021; 15(3):4305–4320. doi: 10.1021/acsnano.0c07440 |
| Froimchuk E, Oakes RS, Kapnick SM, Yanes AA, Jewell CM. Biophysical properties of self-assembled immune signals impact signal processing and the nature of regulatory immune response. Nano Letters. 2021; 21(9), 3762–3771. doi: 10.1021/acs.nanolett.0c05118 |
| Morris AH, Hughes KR, Oakes RS, Cai M, Miller SD, Irani DN, and Shea LD. Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis. Nature Communications. 2020; 11:3871. doi: 10.1038/s41467-020-17629-z |
| Morris AH, Orbach SM, Bushnell GG, Oakes RS, Jeruss JS, and Shea LD. Engineered Niches to Analyze Mechanisms of Metastasis and Guide Precision Medicine. Cancer Research. 2020; 80(18):3786-94. doi: 10.1158/0008-5472.CAN-20-0079 |
| Oakes RS, Bushnell GG, Orbach S, Kandagatla P, Zhang Y, Morris AH, Hall MS, LaFaire P, Decker JT, Hartfield RM, Brooks MD, Wicha MS, Jeruss JS, and Shea LD. Metastatic conditioning of myeloid cells at subcutaneous synthetic niche reflects disease progression and predicts therapeutic outcomes. Cancer Research. 2020; 80(3):602-12. doi: 10.1158/0008-5472.CAN-19-1932 Front Cover – About the Cover Highlight Article from Wolf MT and Elisseeff JH – 10.1158/0008-5472.CAN-19-3631 |
| Dye BR, Youngblood RL, Oakes RS, Kasputis T, Clough DW, Nagy MS, Spence JR, Shea LD. Human lung organoids develop into adult airway-like structures directed by physico-chemical biomaterial properties. Biomaterials. 2020; 234:119757. doi: 10.1016/j.biomaterials.2020.119757 |
| Bushnell GG*, Hong X*, Hartfield RM, Zhang Y, Oakes RS, Rao SS, Jeruss JS, Stegemann JP, Deng CX, Shea LD. High frequency spectral ultrasound imaging to detect metastasis in implanted biomaterial scaffolds. Annals of Biomedical Engineering. 2020; 48:477-489. doi: 10.1007/s10439-019-02366-2 |
| Bushnell GG, Rao SS, Hartfield RM, Zhang Y, Oakes RS, Jeruss JS, Shea LD. Microporous scaffolds loaded with immunomodulatory lentivirus to study the contribution of immune cell populations to tumor cell recruitment in vivo. Biotechnology & Bioengineering. 2020; 117:210-222. doi: 10.1002/bit.27179 |
| Oakes RS, Froimchuk E, Jewell CM. Engineering Biomaterials to Direct Innate Immunity. Advanced Therapeutics. 2019; 2:1800157. doi: 10.1002/adtp.201800157 Selected as Editor’s Choice Article – Advanced Therapeutics Editor’s Choice |
| Bushnell GG, Hardas TP, Hartfield RM, Zhang Y, Oakes RS, Ronquist S, Chen H, Rajapakse I, Wicha MS, Jeruss JS, Shea LD. Biomaterial scaffolds recruit an aggressive population of metastatic tumor cells in vivo. Cancer Research. 2019; 79(8):2042-53. doi: 10.1158/0008-5472.CAN-18-2502 |
| Oakes RS, Jewell CM. A plug-and-play approach for malaria vaccination. Nature Nanotechnology. 2018; 13:1096–97. doi: 10.1038/s41565-018-0291-z |
| Rios PD, Kniazeva E, Lee HC, Xiao S, Oakes RS, Saito E, Jeruss JS, Shikanov A, Woodruff TK, Shea LD. Retrievable hydrogels for ovarian follicle transplantation and oocyte collection. Biotechnology & Bioengineering. 2018; 119:2075-86. doi: 10.1002/bit.26721 |
| Aguado BA, Hartfield RM, Bushnell GG, Decker JT, Azarin SM, Nanavati D, Schipma MJ, Rao SS, Oakes RS, Zhang Y, Jeruss JS, Shea LD. Biomaterial Scaffolds as Pre-metastatic Niche Mimics Systemically Alter the Primary Tumor and Tumor Microenvironment. Advanced Healthcare Materials. 2018; 7(10):e1700903. doi: 10.1002/adhm.201700903 Inside Front Cover Highlight – 10.1002/adhm.201870040 |
| Tarasewicz E‡, Oakes RS‡, Aviles MO, Straehla J, Chilton KM, Decker JT, Wu J, Shea LD, Jeruss JS. Embryonic stem cell secreted factors decrease invasiveness of triple-negative breast cancer cells through regulome modulation. Cancer Biology & Therapy. 2018; 19(4):271-81. doi: 10.1080/15384047.2017.1385681 ‡ Equal Contributors |
| Oakes RS, Polei MD, Skousen JL, Tresco PA. An astrocyte derived extracellular matrix coating reduces astrogliosis surrounding chronically implanted microelectrode arrays in rat cortex. Biomaterials. 2018; 154:1-11. doi: 10.1016/j.biomaterials.2017.10.001 |
Oakes Research Laboratory 